Jorma Ilonen Selected Research

Cytokines

1/2023	Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression.
1/2022	Higher circulating EGF levels associate with a decreased risk of IgE sensitization in young children.
1/2020	Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life.
12/2019	Interleukin-7, T helper 1, and regulatory T-cell activity-related cytokines are increased during the second trimester of healthy pregnancy compared to non-pregnant women.
8/2008	Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant.
6/2007	Reduced CCR4, interleukin-13 and GATA-3 up-regulation in response to type 2 cytokines of cord blood T lymphocytes in infants at genetic risk of type 1 diabetes.
11/2006	Diminished IFN-gamma response to diabetes-associated autoantigens in children at diagnosis and during follow up of type 1 diabetes.

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Jorma Ilonen Research Topics

Disease

182	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/2024 - 01/2002
26	Infections 01/2023 - 01/2003
17	Celiac Disease (Celiac Sprue) 12/2020 - 08/2002
12	Genetic Predisposition to Disease (Genetic Predisposition) 11/2023 - 03/2003
12	Disease Susceptibility (Diathesis) 09/2022 - 02/2004
11	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 05/2002
9	Hypersensitivity (Allergy) 01/2022 - 01/2010
8	Asthma (Bronchial Asthma) 10/2022 - 12/2011
8	Enterovirus Infections 10/2022 - 01/2003
7	Virus Diseases (Viral Diseases) 01/2020 - 08/2006
6	Insulinoma 01/2021 - 01/2007
5	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2023 - 11/2011
5	Milk Hypersensitivity (Milk Allergy) 10/2022 - 08/2014
3	Type 2 Diabetes Mellitus (MODY) 01/2023 - 01/2009
3	Glucose Intolerance 09/2022 - 08/2015
3	Disease Progression 01/2019 - 01/2015
2	Allergic Rhinitis 10/2022 - 01/2013
2	Birth Weight (Birth Weights) 01/2021 - 07/2012
2	Inflammation (Inflammations) 01/2020 - 04/2013
2	Adenoviridae Infections (Adenovirus Infections) 01/2020 - 08/2006
2	Bacterial Infections (Bacterial Infection) 01/2015 - 06/2011
2	Insulin Resistance 10/2013 - 01/2009
2	Otitis Media 11/2011 - 07/2008
2	Multiple Sclerosis 06/2011 - 03/2003
2	Rheumatoid Arthritis 06/2007 - 04/2002
1	Genetic Risk Score 01/2023
1	COVID-19 01/2023

Drug/Important Bio-Agent (IBA)

103	AutoantibodiesIBA 05/2024 - 01/2002
44	Insulin (Novolin)FDA Link 05/2024 - 05/2002
35	AntibodiesIBA 05/2024 - 06/2003
32	1,3-di(4-imidazolinophenoxyl)propaneIBA 12/2023 - 01/2003
20	Proteins (Proteins, Gene)FDA Link 10/2022 - 05/2002
19	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 09/2006
15	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 05/2024 - 06/2003
15	AntigensIBA 11/2020 - 08/2002
13	Immunoglobulin G (IgG)IBA 01/2020 - 02/2004
12	HLA-DR Antigens (HLA-DR)IBA 11/2023 - 09/2003
12	HLA-DQB1 antigen (HLA DQB1)IBA 11/2023 - 03/2002
10	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 02/2013
8	Fatty Acids (Saturated Fatty Acids)IBA 03/2023 - 12/2011
8	HLA-DQ Antigens (HLA-DQ)IBA 01/2023 - 01/2005
7	CytokinesIBA 01/2023 - 11/2006
7	Biomarkers (Surrogate Marker)IBA 01/2023 - 02/2013
7	Immunoglobulin E (IgE)IBA 11/2021 - 01/2010
6	Peptides (Polypeptides)IBA 01/2023 - 02/2004
6	RNA (Ribonucleic Acid)IBA 10/2022 - 11/2007
6	Protein Glutamine gamma Glutamyltransferase 2IBA 01/2020 - 06/2003
6	Immunoglobulin A (IgA)IBA 01/2020 - 09/2007
5	VaccinesIBA 01/2023 - 11/2011
5	Zinc Transporter 8IBA 01/2021 - 11/2010
5	Glutens (Glutelin)IBA 01/2020 - 08/2006
5	GliadinIBA 01/2016 - 08/2006
5	AutoantigensIBA 01/2012 - 05/2002
4	Neutralizing AntibodiesIBA 01/2023 - 02/2004
4	Dietary ProteinsIBA 10/2019 - 11/2010
4	Vitamin D FDA LinkGeneric 01/2019 - 01/2016
4	AllergensIBA 05/2011 - 01/2010
4	EpitopesIBA 07/2008 - 04/2002
3	C-PeptideIBA 01/2023 - 11/2006
3	Amino Acids FDA Link 01/2023 - 12/2008
3	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 10/2022 - 12/2011
3	ProinsulinIBA 01/2020 - 11/2005
3	25-hydroxyvitamin DIBA 01/2019 - 11/2014
3	EnzymesIBA 01/2019 - 05/2006
3	LipidsIBA 01/2019 - 12/2008
3	casein hydrolysateIBA 01/2018 - 11/2010
3	TransglutaminasesIBA 01/2018 - 10/2005
3	Interleukin-17 (Interleukin 17)IBA 10/2016 - 08/2010
3	Immunoglobulin M (IgM)IBA 04/2014 - 06/2012
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2004 - 03/2003
2	HLA-DRB1*04 antigenIBA 11/2023 - 03/2015
2	SugarsIBA 01/2023 - 12/2019
2	Poliovirus VaccinesIBA 01/2023 - 11/2011
2	alpha-Linolenic Acid (Linolenic Acid)IBA 10/2022 - 12/2011
2	AntioxidantsIBA 01/2021 - 08/2008
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021 - 01/2007
2	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 01/2007
2	HLA-DQA1 antigen (HLA DQA1)IBA 12/2020 - 03/2015
2	Phospholipids (Phosphatides)FDA LinkGeneric 10/2020 - 09/2013
2	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2020 - 04/2013
2	Chemokine ReceptorsIBA 01/2019 - 06/2007
2	hydroxide ionIBA 01/2019 - 11/2014
2	Caseins (Casein)FDA Link 01/2018 - 06/2014
2	Genetic Markers (Genetic Marker)IBA 01/2017 - 01/2013
2	Blood Glucose (Blood Sugar)IBA 10/2016 - 05/2015
2	Complement System Proteins (Complement)IBA 01/2016 - 05/2015
2	HLA-DRB1 Chains (HLA DRB1)IBA 03/2015 - 04/2002
2	Palmitic Acid (Hexadecanoic Acid)IBA 03/2014 - 12/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2008 - 09/2003
2	SelectinsIBA 05/2006 - 01/2004
2	Messenger RNA (mRNA)IBA 04/2006 - 09/2003
2	Protein Tyrosine PhosphatasesIBA 03/2005 - 06/2003
1	CholesterolIBA 01/2023
1	LigandsIBA 01/2023
1	interleukin-21 (interleukin 21)IBA 01/2023
1	Quinic Acid (Quinate)IBA 01/2023
1	HexosesIBA 01/2023
1	Glutamic Acid (Glutamate)FDA Link 01/2023
1	adenovirus receptorIBA 01/2023

Therapy/Procedure

3	Therapeutics 01/2018 - 04/2002